Supporting market access through health economic evaluations, understanding value proposition, economic impact and pricing

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Health Technology Assessments

Having the right arguments for demonstrating health and cost impact of your innovation is essential for success. Our team includes professionally qualified and experienced health economists who can provide comprehensive health economic assessments and evaluations to support your innovation. Health Tech Enterprise provides a range of offerings to ensure you have the right kind of evidence to convince decision makers and provide health economic evaluations and, tailor-made to your requirements at each stage of technology development.

Service Offerings:

Evidence Synthesis & Literature Reviews

Reviewing the existing body of published work is a key part in planning for your market access strategy and a crucial cornerstone of evidence-based medicine. Full Health Technology Assessments (HTAs) by NICE require a systematic literature review to be part of the submission.

  • Systematic Literature Reviews (SLR)
    Considered the gold-standard of reviews, which critically evaluates and interprets all the available study evidence relevant to a particular question. Systematic Literature Reviews form the comprehensive evidence base needed for Health Technology Assessment (HTA) and are expected by regulators and publishers.
  • Pragmatic Literature Review
    Adapts the conventional systematic review process to take into consideration limited time and resources available. It uses a streamlined methodology to accelerate the review process and focuses on finding the right evidence to address urgent issues or to inform data parameters for an early-stage health economic model.
  • Meta Analysis & Network Meta Analysis
    Meta analysis uses statistical approaches to combine the results from a collection of studies to answer a specific question. A network meta-analysis is a pairwise meta-analysis to allow comparison of more than two interventions by using direct and indirect evidence. Depending on the quality of the studies available, a meta-analysis can reduce costs by avoiding unnecessary clinical trials.
  • Scoping Reviews
    Used to explore the breadth and extent of all the published evidence available, identify key concepts and research gaps in the research to inform objective setting for future research. Rather than extracting and analysing results, this review maps the landscape of available data.

HTA Support & Evidence Appraisal

  • HTA submission
    As well as preparing the HTA submission document, we can integrate systematic literature reviews, evidence synthesis and economic modelling into your HTA submission for approval by the regulatory agency
  • Critical Appraisal of HTA submissions & research results
    We can perform critical appraisals of your HTA submissions and  your research results to identify areas of uncertainty, potential risks of bias and confounding and provide recommendations on how to address these.
  • Review of Reviews
    Reviews and critically appraises the quality of existing systematic literature reviews in a specific field to assess risks of bias, differences in methodologies and the impact this may have had on the findings.

Health Economics & Decision Modelling

To gain market access to the NHS it is essential to quantify properties, effects, costs and impacts of the new health technology. As well as clinical evidence, these need to present the economic evidence and the incremental health benefit which can be achieved in relation to costs as part of a Health Economic Assessment.

HTE can provide a range of Assessments, appropriate to each stage of technology development

  • Budget Impact Analysis
    Often used at an early -stage investigation to determine the impact of a technology on a specific budget (e.g. NHS, Health insurance plan). This type of analysis is concerned with assessing the affordability of the technology from the perspective of a designated budget holder.
  • Cost-effectiveness Analysis
    A full model assesses the relative cost-effectiveness of the new technology as compared to current care. A CEA provides impact evidence required by NHS and PSS budget holders and is an essential component of a Health Technology Assessment (HTA) application. This type of analysis  models both current and new care pathways for the addressable market population and often includes a systematic literature review to identify data for parameter inputs. The analysis compares the cost in monetary units with outcomes using a generic measure of utility-weighted health outcome (e.g. QALYs) as per the NICE reference case.
  • Cost Consequences Analysis
    Alternative to a cost-effectiveness analysis when measures of effect have not yet been quantified. A less prescriptive form of cost-effectiveness analysis, this is often used to strengthen funding applications. The analysis models both current and new care pathways for the addressable market population, comparing costs against discrete categories of outcomes which do not require utility weighting (e.g. presented as monetary savings, health outcomes in natural units or condition-specific outcomes).  Outcomes tend to be presented in a non-aggregated form.
  • Visual customer communication tools
    Design of user-friendly visual representations of the outputs from Health Economic Evaluations to communicate the value of your innovation to potential customers and budget holders.

Training & Mentoring

We can offer additional training and support on a variety of topics from an introductory course to more specialist courses on how to get the best use out of your model.

  • Training courses in health economics (virtual & F2F)
    We deliver customised training courses in different areas of health economics, from introductory sessions requiring no prior knowledge to more specialist sessions introducing the audience a specific technique.
  • Training of payor-facing teams
    We train your payor-facing team to the use the developed, fully interactive model when facing budget holders.
  • Mentoring & support
    We offer mentoring and support to clients who would like to build up their health economic skills and assist them every step of the way.

Attend our 'Essentials in Health Economics' Course

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